文春根

文春根 教授、博士生导师

研究方向:水生生物学

主要荣誉及专业团队任职:江西省高校中青年学科带头人,水

产动物免疫与营养团队负责人。

邮箱:cgwen@ncu.edu.cn

教育经历:

11983-1987 山东海洋学院 (现中国海洋大学) 水产养殖学 本科

21989-1991 江西大学 (现南昌大学) 动物学 硕士

32002-2005 中国科学院水生生物研究所 水生生物学 博士

工作经历:

11987- 南昌大学 教师

执教课程:

本科生课程:水产动物疾病防治,水化学,发育生物学。

研究生课程:水生生物学,水生生物技术。

主持课题项目:

1、长江中下游大型湖泊贝类寄生蚌区系及其系统发育研究,国家自然科学基金 (面上项目,30571434)2006-2008年。

2、褶纹冠蚌抗氧化系统对微囊藻毒素胁迫的响应及抗氧化酶基因的克隆与功能研究,国家自然科学基金 (地区项目,30960296)2010-2012年。

3、贝类 Nrf2/Keap1 信号通路参与消减微囊藻素毒性的分子机制,国家自然科学基金 (面上项目,31472305)2015-2018年。

4、镉诱导大鼠睾丸支持细胞凋亡和DNA甲基化的作用机制研究,国家自然科学基金 (地区项目,21467015)2015-2018年。

5TGF-β/Smads信号通路导基质金属蛋白酶在三角帆蚌伤口修复中的作用研究,国家自然科学基金 (地区项目,31460697)2015-2018年。

主要学术贡献及奖励:

1、研究了水产动物寄生虫、非特异性免疫。包括水产动物寄生虫的鉴定与分类、生态、系统发育以及水产动物抗氧化酶、溶菌酶等非特异性免疫因子基因和蛋白功能。

2、中国蚌区系及系统进化研究,江西省自然科学奖,三等奖,2014年。

代表性论文:

1Population dynamics of the water mite Unionicola arcuata (Unionicolidae) in the freshwater bivalve Cristaria plicata (Unionidae) in Poyang Lake, eastern China. Diseases of Aquatic Organisms2006721-2):123-127

2A new species of the genus Unioniocola from China (Acari: Unionicolidae). Systematic and Applied Acarology; 1998;3:171-174

3Sequence variation of the mitochondrial 12S rRNA gene among Unionicola (Wolcottatax) arcuata (Acari: Unionicolidae) from freshwater mussels in China. International Journal of Acarology, 2012, 38(5): 394401.

4Molecular cloning, identification and functional characterization of a novel intracellular Cu/Zn superoxide dismutase from the freshwater mussel Cristaria plicata. Fish & Shellfish Immunology, 2010, 29: 615-622.

5Morphology and phagocytic ability of hemocytes from Cristaria plicata. Aquaculture, 2011, 310: 245251.

6A catalase from the freshwater mussel Cristaria plicata with cloning, identification and protein characterization. Fish & Shellfish Immunology, 2011, 31: 389-399.

7Cloning, identification and functional characterization of a pi-class glutathione S-transferase from the freshwater mussel Cristaria plicata. Fish & Shellfish Immunology, 2012, 32(1): 51-60.

8Gene identification and recombinant protein of a lysozyme from freshwater mussel Cristaria plicata. Fish & Shellfish Immunology, 2013, 34(5): 1033-1041.

9Cloning and expression of Selenoprotein W from Pearl mussels Cristaria plicata. Comparative Biochemistry and Physiology, Part B, 2014,167 (1): 815.

10Molecular cloning and characterization of cathepsin L from freshwater mussel, Cristaria plicata. Fish & Shellfish Immunology, 2014, 40: 446-454.

11Molecular cloning and functional characterization of a novel i-type lysozyme in freshwater mussel Cristaria plicata. Microbiology and Immunology, 2015, 59: 744755.

12Identification and characterization of two LBP/BPI genes involved in innate immunity from Hyriopsis cumingii. Fish & Shellfish Immunology, 2017, 60(1): 436-446.

13 Molecular cloning, expression and antioxidative activity of 2-cys-peroxiredoxin from freshwater mussel Cristaria plicata. Fish & Shellfish Immunology, 2017, 66(1): 254-263.

14Molecular characterization of two distinct Smads gene and their roles in the response to bacteria change and wound healing from Hyriopsis cumingii. Fish & Shellfish Immunology, 2017, 67: 129-140.

15Seasonal variation of a population Unionicola penicillatus (Unionicolidae) from the freshwater bivalve Cristaria plicata (Unionidae) in Poyang Lake, eastern China. Systematic & Applied Acarology 2018, 23(2): 288295.

16Microcystin induction small Maf protein involve in transcriptional regulation of GST from freshwater mussel Cristaria plicata. Gene, 2018, 660 (03-04): 5161.

17Identification and characterization of two distinct sigma-class glutathione-Stransferase from freshwater bivalve Cristaria plicata. Comparative Biochemistry and Physiology, Part B, 2018, 660 (219-220): 5261.

18Identification and expression of cathepsin B from the freshwater mussel Cristaria plicata. Comparative Biochemistry and Physiology, Part B, 2018 (225): 2128.