胡宝庆 教授、硕士生导师

研究方向：水产动物免疫与疾病

主要荣誉及专业团队任职：江西省水产学会理事，江西省科技特派员

邮箱：baoqinghu@sina.com

教育经历：

工作经历：

1、2022.12-迄今 南昌大学生命科学学院，教授

执教课程：

主持课题项目：

2、TGF-β/Smads信号通路介导基质金属蛋白酶在三角帆蚌伤口修复中的作用研究， 国家自然基金，2015-01 — 2018-12.

3、江西省现代农业产业技术体系：江西省大宗淡水鱼产业技术体系病虫害防控岗位专家，2022-01—

3、明胶酶及其抑制剂在三角帆蚌伤口修复中的作用研究， 江西省自然科学基金，2015-01 — 2017-12.

4、重组三角帆蚌LBP/BPI 的杀菌功能分析及其在珍珠养殖中的应用， 江西省农业科技支撑计划，2015-01 — 2017-12.

5、褶纹冠蚌溶菌酶及其在抗菌免疫中的作用， 江西省自然科学基金，2013-01 — 2015-12.

6、淡水育珠蚌溶菌酶基因克隆及其体外表达产物活性研究， 江西省教育厅项目，2010-01 — 2012-12.

7、三角帆蚌非特异性免疫因子的克隆， 江西省自然科学基金，2007-01 — 2009-12.

主要学术贡献及奖励：

代表性论文：

1. Cao X, Lu W, Gang Y, Hu B, Wen C. Prx5 of Cristaria plicata has antioxidant function and is regulated by Nrf2/ARE signaling pathway. Fish Shellfish Immunol. 2023;134:108548.（通讯作者）

2. Wang C, Hu H, Zeng L, Ni C, An J, Gang Y, Jian S, Wen C, Hu B. MafG-like contribute to copper and cadmium induced antioxidant response by regulating antioxidant enzyme in Procambarus clarkii. Gene.2022;847:146848.（通讯作者）

3. An J, Cao X, Feng M, Hu B, Wu J, Gang Y, Jian S, Wen C. MAPK/MAK/MRK overlapping kinase mediated apoptosis through caspase signaling pathway from Cristaria plicata. Dev Comp Immunol. 2022; 133:104427.

4. ShaoQing Jian, JiangHe Leng, ZiYi Wen, HaiYang Luo, ChengXi Hu, ChunGen Wen, BaoQing Hu*. β-arrestin interacts with TRAF6 to negatively regulate the NF-κB pathway in triangle sail mussel Hyriopsis cumingii. Fish and Shellfish Immunology, 2022,127:65-73. 通讯作者

5. Zhu M, Su F, Leng J, Jian S, Yi P, Wen C, Hu B. Two NF-κB subunits are associated with antimicrobial immunity in Hyriopsis cumingii. Dev Comp Immunol. 2022;129:104336. 通讯作者

6. Jinhua An, Chengli Wang, Shaoqing Jian, Yang Gang, Chungen Wen*, Baoqing Hu*. Construction of wound repair model and function of recombinant TIMP from Hyriopsis cumingii. Fish and Shellfish Immunology. 2021, 119 533-541. 通讯作者,

7. ShuYuan Yin, Jian Chen, MingXing Zhu, BaoQingHu*. Characterization of a novel toll-like receptor and activation NF-κB signal pathway in triangle sail mussel Hyriopsis cumingii. Comparative Biochemistry and Physiology, Part B. 2021, 255, 110608. 通讯作者

8. Zhenfang Li, Ming xing Zhu, Baoqing Hu, Effects of suppressing Smads expression on wound healing in Hyriopsis cumingii. Fish and Shellfish Immunology.2020,97 455-464. 通讯作者

9. Baoqing Hu* , Jun Xiao, Peipei Yi et al., Cloning and characteristic of MMP1 gene from Hyriopsis cumingii and collagen hydrolytic activity of its recombinant protein. Gene, 2019. 693:92-100.

10. Zhenfang Li, Yuduan Cha, Baoqing Hu*et al., Identification and characterization of two distinct sigma-class glutathione-S-transferase from freshwater bivalve Cristaria plicata. Comparative Biochemistry and Physiology, Part B.2018, 219-220:52-56. 通讯作者

11. Peipei Yi,Xiaojuan Hu, Baoqing Hu* et al., Identification and expression of cathepsin B from the freshwater mussel Cristaria plicata. Comparative Biochemistry and Physiology, Part B. 2018, 225:21-28. 通讯作者

12. Xiaobo Wang, Jielian Wu, Shaoqing Jian, Gang Yang, Baoqing Hu*, Chungen Wen*. Microcystin induction small Maf protein involve in transcriptional regulation of GST from freshwater mussel Cristaria plicata.Gene.2018, 660:51-61. 通讯作者

13.Baoqing Hu, Chungen Wen*, Ming Zhang et al., Identification and characterization of two LBP/BPI genes involved in innate immunity from Hyriopsis cumingii. Fish and Shellfish Immunology. 2017, 60:436-446.

14. Baoqing Hu*, Peipei Yi, Zhenfang Li,et al., Molecular characterization of two distinct Smads gene and their roles in the response to bacteria change and wound healing from Hyriopsis cumingii. Fish & Shellfish Immunology.2017, 67:129-140.

15. Xiaobo Wang, Baoqing Hu, Chungen Wen* et al., Molecular cloning, expression and antioxidative activity of 2-cys-peroxiredoxin from freshwater mussel Cristaria plicata. Fish & Shellfish Immunology. 2017, 66:254-263.

16. W Jielian, H Baoqing, W Chungen, Y Peipei. Characterization and roles of lysozyme in molluscs.2017, ISJ 14:432-442.