潘秉兴
时间：2019-10-16 08:30:00 来源：作者：
潘秉兴 医学博士、研究员、国家级人才、校级人才、博士生导师
研究方向：焦虑障碍的发病机制与防治策略
主要荣誉及专业团队任职：国家级人才、省部级人才；中国生理学会常务理事、应激生理学专委会副主任委员；中国神经科学学会应激神经生物学分会副主任委员；任Neuroscience and Biobehavioral Reviews、Frontiers in Cellular Neuroscience编委、Stress and Brain副主编等。
邮箱：panbingxing@ncu.edu.cn
主持课题项目：
1、 国家自然科学基金杰出青年项目：应激致情感障碍的脑机制【批准号：82125010；起止时间：2022-2026】
2、 科技部2030重大研究计划项目：恐惧情绪调控的内侧前额叶皮层神经环路机制研究【批准号：2021ZD0202704；起止时间：2022-2026】
3、 国家自然科学基金重点项目：慢性应激致焦虑障碍的杏仁核环路与分子机制【批准号：81930032；起止时间：2020-2024】
4、 国家自然科学基金面上项目：基于杏仁核神经元的投射靶区研究慢性应激引发焦虑障碍的机制【批准号：81771459；起止时间：2018-2021】
5、 国家自然科学基金重大研究计划培育项目：外侧杏仁核含δ亚基GABAA 受体在调控皮层-杏仁核环路信息传递中的作用及机制研究【批准号：2015AA016106；起止时间：2014-2016】
6、国家级项目：情绪调控知觉学习的神经机制研究【批准号：2014CB846100；起止时间：2014-2018】
代表性论文：
1. Xia Qin, Han-Qing Pan, Shou-He Huang, Jia-Xin Zou, Zhi-Heng Zheng, Xiao-Xuan Liu, Wen-Jie You, Zhi-Peng Liu, Jun-Li Cao, Wen-Hua Zhang, Bing-Xing Pan. GABAA(δ) receptor hypofunction in the amygdala-hippocampal circuit underlies stress-induced anxiety. Science Bulletin, 2022. 67:97-110. （通讯作者）
2. Wen-Hua Zhang, Jun-Yu Zhang, Andrew Holmes, Bing-Xing Pan. Amygdala circuit substrates for stress adaptation and adversity. Biological Psychiatry, 2021, 89:847-856. (Cover) (Invited Review)（通讯作者）
3. Peng Chen, Hong-Yang Jing, Ming-Tao Xiong, Qian Zhang, Dong Lin, Dong-Yan Ren, Shun-Qi Wang, Dong-Min Yin, Yong-Jun Chen, Tian Zhou, Bao-Ming Li, Er-Kang Fei, Bing-Xing Pan. Spine impairment in mice high-expressing neuregulin 1 due to LIMK1 activation. Cell Death and Disease, 2021, 12:403.（通讯作者）
4. Shou-He Huang, Wei-Zhu Liu, Xia Qin, Chen-Yi Guo, Qing-Cheng Xiong, Yu Wang, Ping Hu, Bing-Xing Pan, Wen-Hua Zhang. Association of Increased Amygdala Activity with Stress-Induced Anxiety but not Social Avoidance Behavior in Mice. Neuroscience Bulletin, 2021.（通讯作者）
5. Tian-Kun Hui, Xin-Sheng Lai, Xia Dong, Hong-Yang Jing, Zi-Yang Liu, Er-Kang Fei, Wen-Bing Chen, Shun-Qi Wang, Dong-Yan Ren, Su-Qi Zou, Hai-Tao Wu, Bing-Xing Pan. Ablation of Lrp4 in Schwann Cells Promotes Peripheral Nerve Regeneration in Mice. Biology, 2021, 10:452.（通讯作者）
6. Peng Chen, Zi-Yang Liu, Qian Zhang, Dong Lin, Song Lu, Jiang-Hong Liu, Hui-Feng Jiao, Xin-Sheng Lai, Su-Qi Zou, Shun-Qi Wang, Tian Zhou, Bao-Ming Li, Li Zhu, Bing-Xing Pan, Er-Kang Fei. DSCAM deficiency leads to premature spine maturation and autism-like behaviors. Journal of Neuroscience, 2021, https://doi.org/10.1523/JNEUROSCI.1003-21.2021（通讯作者）
7. Yu Liu, Ping Hu, Zhi-Heng Zheng, Da Zhong, Wei-Chang Xie, Zhi-Bo Tang, Bing-Xing Pan, Jun Luo, Wen-Hua Zhang, Xiao-Lei Wang. Photoresponsive Vaccine-Like CAR-M System with High-Efficiency Central Immune Regulation for Inflammation-related Depression. Advanced Materials, 2021, e2108525. Advance online publication.（通讯作者）
8. Wen-Bing Chen, Han-Qing Pan, Ye He, Xue-Hui Wang, Wen-Hua Zhang, Bing-Xing Pan. Rap1b but not Rap1a in the forebrain is required for learned fear. Cell and Bioscience, 2020, 10:107.（通讯作者）
9. Han-Qing Pan, Wen-Hua Zhang, Cai-Zhi Liao, Ye He, Zhi-Ming Xiao, Xia-Qin, Wei-Zhu Liu, Na Wang, Jia-Xin Zou, Xiao-Xuan Liu, Bing-Xing Pan. Chronic stress oppositely regulates tonic inhibition in Thy1-expressing and non-expressing neurons in amygdala. Frontiers in Neuroscience, 2020, 14:299. （通讯作者）
10. Wei-Zhu Liu, Wen-Hua Zhang, Zhi-Heng Zheng, Jia-Xin Zou, Xiao-Xuan Liu, Shou-He Huang, Wen-Jie You, Ye He, Jun-Yu Zhang, Xiao-Dong Wang, Bing-Xing Pan. Identification of a prefrontal cortex-to-amygdala pathway for chronic stress-induced anxiety. Nature Communications, 2020, 11:2221（通讯作者）
11. Ren-Wen Han, Zhi-Peng Liu, Hong-Ru Lin, Ao-Wen Tian, Yun-Fei Xiao, Jie Wei, Ke-Yu Deng, Bing-Xing Pan, Hong-Bo Xin. Role of Lateral Amygdala calstabin2 in Regulation of Fear Memory. Molecular Brain, 2020, 13(1):35. （通讯作者）
12. Wen-Hua Zhang, Wei-Zhu Liu, Ye He, Wen-Jie You, Jun-Yu Zhang, Hong Xu, Xiao-Li Tian, Bao-Ming Li, Lin Mei, Andrew Holmes, Bing-Xing Pan#. Chronic stress causes projection-specific adaptation of amygdala neurons via small-conductance calcium-activated potassium channel downregulation. Biological Psychiatry, 2019, 85:812-828.（通讯作者）
13. Jun-Yu Zhang, Tao-Hui Liu, Ye He, Han-Qing Pan, Wen-Hua Zhang, Xiao-Li Tian, Xiao-Ping Yin, Bao-Ming Li, Xiao-Dong Wang, Andrew Holmes, Ti-Fei Yuan, Bing-Xing Pan. Chronic stress remodels synapses in an amygdala circuit-specific manner. Biological Psychiatry, 2019, 85:189-201.（通讯作者）
14. Wen-Hua Zhang, Ke-Xin Cao, Zeng-Bo Ding, Jian-Li Yang, Bing-Xing Pan, Yan-Xue Xue. Role of prefrontal cortex in extinction of drug memories. Psychopharmacology. 2019. 236: 463-477. (Invited Review) （通讯作者）
15. Xiao-Bin Xu, Shi-Jun Fan, Yuan-Qiao Guo, Ruei Tan, Jun-Yu Zhang, Wen-Hua Zhang, Bing-Xing Pan, Nobumasa Kato. The effects of perinatal bisphenol A exposure on thyroid hormone homeostasis and glucose metabolism in prefrontal cortex and hippocampus of rats. Brain & Behavior. 2019. e01225.（通讯作者）
16. Xiao-Bin Xu, Shi-Jun Fan, Yuan-Qiao Guo, Ruei Tan, Jun-Yu Zhang, Wen-Hua Zhang, Bing-Xing Pan, Nobumasa Kato. The effects of perinatal bisphenol A exposure on thyroid hormone homeostasis and glucose metabolism in prefrontal cortex and hippocampus of rats. Brain & Behavior. 2019. e01225. （通讯作者）
17. Zhi-Peng Liu, Qing-Hai He, Han-Qing Pan, Jin Zhou, Ye He, Xiao-Bin Xu, Xiao-Ping Yin, Bao-Ming Li, Tian-Ming Gao, Bing-Xing Pan#. Delta subunit containing GABAA receptors disinhibit lateral amygdala and facilitate fear learning in mice. Biological Psychiatry. 2017, 81(12): 990-1002.（通讯作者）
18. Xiao-Bin Xu, Shi-Jun Fan, Ye He, Wen-Hua Zhang, Bing-Xing Pan. Loss of hippocampal oligodendrocytes contributes to the deficit of contextual fear conditioning in adult rats experiencing early bisphenol A exposure. Molecular Neurobiology. 2017, 54(6):4524-4536. （通讯作者）
19. Chen Song, Wen-Hua Zhang, Xue-Hui Wang, Jun-Yu Zhang, Xiao-Li Tian, Xiao-Ping Yin, Bing-Xing Pan. Acute stress enhances the glutamatergic transmission onto basoamygdala neurons embedded in distinct microcircuits. Molecular Brain. 2017, 10: 3.（通讯作者）
20. Wen-Hua Zhang, Jin Zhou, Han-Qing Pan, Xue-Hui Wang, Wei-Zhu Liu, Jun-Yu Zhang, Xiao-Ping Yin, Bing-Xing Pan. δ Subunit-containing GABAA receptor prevents overgeneralization of fear in adult mice. Learning & Memory. 2017, 24(8):381-384. （通讯作者）